RELATION OF IRON TO NEOPLASTIC DISEASE (1935)
Walter B. Guy, M.D.

It is axiomatic that a healthy organism in either the vegetable or animal world is primarily dependent upon a normal balanced mineral content. Therefore, an excess or a deficiency must inevitably bring about, sooner or later conditions known as disease. That the abnormal mineral content will likewise cause the affected organism to be less able to withstand encroachment of microbic life is likewise a truism.

The writer wishes to present some interesting data linking up both the vegetable and animal worlds showing, by proven statistics, how certain mineral deficiencies disease conditions and how this knowledge applied to neoplastic and affiliated diseases in the human kingdom throws flood of light upon this darkened area of human knowledge; also to show how, when this truth discovered in the vegetable world is applied to cases of cancerous disease, its symptoms can be greatly mitigated and curative results become strikingly manifest.

Twelve years ago, more or less, east of the Mississippi River, corn plants began to die. Their stalks were stunted, molds grew on ears and roots, and farmers were in despair. The sweet corn canning industry was also involved, for black specks would appear in the canned corn, to the disgust of good housewives and the dismay of the canners when this product was returned to the canning factories. Expert chemists examined these black specks and pronounced them precipitated iron particles.

But, how did iron get into the corn and why did these corn plants, roots and ears develop unsightly molds such as the rhiizopus, gibberella, fusarium, etc.?

It was George Hoffer who, with the help of others, finally put the puzzle together. Taking ears of corn, by using the well-known thiocyanate test, he found iron, first, in the grains of corn, before canning; next, in the joints of corn, where it had blocked the channels for sap; also that a weak solution of iron slowly injected into a growing corn plant caused these diseased conditions to appear.

By using the methylene blue stain he noted that the circulation of sap had been almost completely blocked by these iron deposits. At last, after much research, it was found that when potassium salts were applied to the soil these disease phenomena were controlled; also the various molds likewise were no longer found on roots and cars. Again potassium salts increased production two to three hundred per cent in potassium-deficient soils. Can we show that potassium deficiency may be present in animal bodies and, like in corn, this deficiency may cause profound changes in their metabolic life?

Professor A. E. Austin' says that: "Potash salts are believed to be absolutely necessary for the sustenance of life." Again, Professor R. A. Hatcher, says: "It is only within recent times that we have come to understand the importance of extremely small amounts of certain salts of the blood and the influence exerted by even slight changes in its composition. Small amounts of potassium are essential for the heart-beat, etc.'' Of late years we hear of iron precipitation into the kidney and other organs, as in pernicious anemia, and if this precipitation of metallic iron can be shown to be the cause of the indurated (hard) tumors, malignant and benign neoplastic (cancerous) growths, a great step forward can be taken toward ultimate victory over neoplastic malignant disease.

But what test can demonstrate potassium deficiency in human tissues? There is a more or less accurate test for this deficiency in soils; but, after all is said and done, the only real proof is a pragmatic one, viz., what effect does the administration of certain potassium salts have in cases of cancerous disease? Can we show, as in corn production, that this metal does the same to human bodies as it does to growth of this cereal? Does the administration of potassium salts soften indurated (hardened) cancer tissue, pick up again precipitated iron and cause a decisive increase of hemoglobin in anemic blood, cause tumors to reduce in size and bring health and life back to cancer victims? If so, what great possibilities are in sight! For, by simply adding a potassium salt to daily intake of sodium chloride all the varied aspects, and they are many, of this deficiency may be prevented and controlled. As, however, this thesis is devoted to cancer warfare, mention of other disease conditions will be left for some future papers.

What evidence have we that, like as in cases of iron precipitation in corn, shutting off the circulation of sap through the nodes of the plants, in man a blocking of the lymph nodes can be likewise present and cause the phenomena we term neoplasms? First of all I will quote from a letter from Professor W. W. Keen to W. Sampson Handley, M. D., surgeon to Middlesex Hospital, London: "I have just read your very interesting address on 'Lymph Stasis the precursor of Cancer! It appeals to me as the most reasonable and almost certain paper on the origin of cancer that I have ever seen. All others are guesswork. Here is a series of facts, observations which cannot be disputed. . . . Whether we can do anything to prevent or remedy the stasis of lymph or not is the next question. If we can, we can possibly prevent cancer."

Again in the same article Dr. Handley states: "In remarkable accord with the view that lymph stasis is the greatest general physiological factor which lays the foundation of cancer, is the flood of evidence coming from many quarters that papilloma or adenoma is the precursor of carcinoma of every variety." "If, as I maintain, the papilloma or papillary adenoma is the characteristic product of local lymphatic obstruction, we are getting near to the conclusion that all carcinomas are the result of local lymphatic obstruction."

That an excess of one group of minerals and deficiency of another may seriously disturb the delicate pH chemical balance is easily understood; also that this chemical imbalance is present in cancerous disease has been almost universally accepted by the scientific medical authorities.

The late Dr. Willy Meyer, of New York City, wrote. "Exact pH measurements have revealed the fact, as shown by the literature, that malignancy is always associated with a high degree of alkalosis, and it has also been shown that the alkalosis precedes the malignancy. There can be alkalosis without malignancy but it would seem that there can be no malignancy without alkalosis. The more virulent the malignancy. The stronger must be the alkalosis which sustains it."

Calcium magnesium and sodium are seemingly in excess in alkalosis of the body; in the earth calcium, phosphorus and magnesium are recommended for acid soils. Yet potassium is rarely in excess in such soils, but usually deficient, and when corn is destroyed or injured by precipitation of iron into the nodes, roots, ears and leaves of the plant, we always find a deficiency of potassium salts. Likewise in this potassium deficiency disease of corn we find reported that many varieties of molds attack ears and roots. Does this fact not remind us of the varied micro-organisms that are found in all advanced cases of malignant growths and reported by so many research workers?

During the past years a potassium salt solution has been given to quite a few cases of cancer with striking curative results. Since giving potassium salts in a solution of hydrochloric acid of about 2 percent, results are so striking that the before-mentioned claim of result of precipitated iron must be as true in man as in corn, for in as short a space of time as four weeks in a woman of 42 years the writer has seen indurated masses disappear, circulation of the arm restored, infiltrated lung by metastatic growths clear up, blood index rise; strength, color and appetite return; pain relieved and a large hole in right breast under simple germicidal application fill in rapidly with healthy tissue; also involvement of spine with pain in spine and intercostal nerves entirely relieved.

A striking case of keratosis treated in Takoma Park, Md. was that of a woman who had a horny mass on the heel of one foot for over eighteen years. This growth would crack, ulcerate and break away; then another growth would take its place. Six weeks from commencing to take potassium salt solution the foot was well and skin was normal. This case is especially interesting, showing, as it does, how a potassium deficiency may be present many years, and opens up new thought for treatment of not only keratosis, but psoriasis and similar affections, for in keratosis we have a condition closely allied to epithelioma.

In the city of Jacksonville there is a woman about 70 years of age who several years before had her right breast removed and axilla cleaned out for cancerous growth. Last spring the writer examined her and found several large, hard, recurrent growths on the border of the axilla and in the ribs. The potassium and hydrochloric acid solution was prescribed. At this date all these recurrent growths have disappeared and her general health is greatly improved.

Repeated cases have proved that the acid potassium solution changes back to normal the gastric secretion and impaired digestion. The past four years of economic distress and financial worry are already bringing a harvest of degenerative disease, including cancer in all its manifold phenomena. And because of this great demand for relief, the writer puts out this information instead of piling up conclusive proofs for several years in order that others, if they so desire, may use this form of treatment, so inexpensive and yet so successful in the writer's hands.

Apropos of the claim that iron is precipitated into lymph channels, blocking of the affected areas from the lymph circulation and nerve control of cell life, and these blocked lymph areas become a fruitful field for micro-organisms of varied nature and kind to infect these occluded tissues, what further proof can be given to prove this statement? A most suggestive fact repeated over and over again is that in advanced cases of cancerous disease the hemoglobin color index is invariablyl low --- 40 to 50% an the color chart. After such cases have been treated a week or two, even when no iron is administered the color index is found to have risen to 70 or 80%. This indicates, the author believes, that the red cells of blood have taken up the precipitated iron which they had lost by the potassium deficiency. This phenomenon throws new light on the various anemias of blood so hard and unsatisfactory to treat, and also on the solution of the problem, for if iron is precipitated into the tissues it seemingly must have been lost by the hemoglobin of the red corpuscles, and, if they regain it, this engorged tissue should be dissipated. This is exactly the phenomenon that occurs when HCl and potassium are taken or, better, injected into the blood stream. The cancerous indurated growths often then disappear and the hemoglobin color index rises nearer to the normal.

Various means have been employed to combat alkalosis, mostly futile, others quite injurious. In soils calcium is applied to combat acidosis, and, when given to cancer cases by the author, has proved most disastrous. Magnesium salts likewise. The hydrochloric acid solution with potassium salts, by vein and mouth, however, is most effective. The ammoniacal urine present in advanced cancer soon becomes acid, accompanying the dissolution of swollen lymph nodes and improvement of blood, etc.

The addition of hydrochloric acid to the body increases the available chlorine, with its marked antiseptic and phagocytic properties; also it helps to restore the normal pH of the tissues.

Starvation also tends to correct alkalosis, but it cannot do much to relieve accompanying toxemia. Loss of blood likewise also helps greatly, in the writer's experience, in removing excess of iron, and many report themselves improved in health after losing blood from hemorrhoids, kidneys, liver,etc.

NOTE by Loren Parks: Excess potassium can cause heart stoppage. Dr. Kervorkian used it intravenously for that to assist suicide. A potassium pill with a meal is probably OK. Melons, fruits and vegetables are rich in potassium. Many cancer cures are attributed to going on a total vegetable/fruit juice diet (Breuss). Remember, this article was written during the depths of the depression, and malnutrition among the poor was rampant.

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